For retrieving and updating data the same ideas apply. In addition, you need to use scroll() to take advantage of server-side cursors for queries that return many rows of data.

Session session = sessionFactory.openSession();
Transaction tx = session.beginTransaction();
   
ScrollableResults customers = session.getNamedQuery("GetCustomers")
    .setCacheMode(CacheMode.IGNORE)
    .scroll(ScrollMode.FORWARD_ONLY);
int count=0;
while ( customers.next() ) {
    Customer customer = (Customer) customers.get(0);
    customer.updateStuff(...);
    if ( ++count % 20 == 0 ) {
        //flush a batch of updates and release memory:
        session.flush();
        session.clear();
    }
}
   
tx.commit();
session.close();